Virtuelles lineal online dating magical girl lyrical nanoha movie 2nd online dating

Living with HIV makes considerable demands on a person in terms of self-management, especially as regards adherence to treatment and coping with adverse side-effects.

Participants must be aged 18 years or older, have been on ART for at least 6 months, and have internet access.The intervention is composed of four interactive computer sessions of 20 to 30 minutes hosted by a virtual nurse who engages the PLHIV in a skills-learning process aimed at improving self-management of medication intake.Adherence constitutes the principal outcome, and is defined as the intake of at least 95% of the prescribed tablets.The following intermediary measures will be assessed: self-efficacy and attitude towards antiretroviral medication, symptom-related discomfort, and emotional support.However, adherence to treatment is key to preventing treatment failure and the development of antiviral drug resistance.

A certain degree of non-adherence might have an effect on treatment outcome, depending on pattern and medication.For example, individuals who skip treatment on consecutive days (sustained interruption) are at higher risk of presenting a detectable viral load than are those who skip an equal number of doses non-consecutively (interspersed missed doses) [].Furthermore, it has been recognized that, because of their long half-lives and potency, certain types of medication, such as non-nucleoside reverse-transcriptase inhibitors (NNRTIs) and boosted protease inhibitors (PIs), are more forgiving of moderate levels of adherence [Treatment adherence immediately arose as a key issue after the introduction of ART.There will be three measurement times: baseline (T0), after 3 months (T3) and 6 months (T6) of baseline measurement.The principal analyses will focus on comparing the two groups in terms of treatment adherence at the end of follow-up at T6.An intention-to-treat (ITT) analysis will be carried out to evaluate the true value of the intervention in a real context.